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Myelophthisic Anemia – What to Expect From a Myelophthisic Anemia Diagnostic Evaluation


Myelophthisic anemia is an anemic condition caused by damage which is done to the tissue of the bone marrow when it is invaded by certain types of infections and cancers. This causes abnormal tissue to be formed which prevents a sufficient amount of red blood cells and platelets from being produced by the bone marrow.

The white blood cell count may remain normal or can increase. When the level of red blood cells and platelets are low, this results in low oxygen levels within the body and abnormal bleeding can occur.

Symptoms and Diagnosis of Myelophthisic Anemia

Symptoms which may suggest the presence of myelophthisic anemia include tiredness, fatigue, dizziness, rapid heartbeat, chest pain, and shortness of breath. These symptoms may also be accompanied by a fever indicating an infection. During a physical examination the physician will look at the skin and fingernails for paleness in color, bruising or bleeding under the skin as well as a rapid heartbeat or “tachycardia”.

A blood test will be ordered and if an anemic condition is present this will show with a significantly low number of red blood cells and platelets. These cells-including the white blood cells-will then be examined microscopically to determine if their shape and size matches the characteristics of cells found in myelophthisic anemia. Further testing may then be done with a microscopic examination of the bone tissue to determine what condition is causing this tissue to be damaged.

Treatment of Myelophthisic Anemia

Treatment for this type of anemia is primarily focused on what has caused this condition. In cases of the tissue being damaged by infections such as a fungus or tuberculosis, the anemia typically disappears on its own once the underlying condition is treated. If the anemia is caused by a type of cancer, blood transfusions may be necessary to elevate the blood levels during treatments such as radiation and chemotherapy. In some cases of myelophthisic anemia, the spleen becomes enlarged and may have to be surgically removed.

Source by Anne Ahira

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